Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL21683086

CCCCCCCC/C=C\CCCCCCCC(C)(C)N.N

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.48
TRPV1 Q8NER1 1/20 0.48
SOAT1 P35610 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C19 P33261 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
KDM4E B2RXH2 2/20 0.43
TERT O14746 3/20 0.42
MAPT P10636 2/20 0.42
BLM P54132 2/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 2/20 0.42
GMNN O75496 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211940 0.98 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9211167 0.98 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9210560 0.98 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL165447 0.98 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9202958 0.98 FAAH (0.50) FAAHTRPV1SOAT1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL9484019 0.96 FAAH (0.48) FAAHTRPV1SOAT1CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL11151898 0.96 FAAH (0.48) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9207284 0.94 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9206537 0.94 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19
SCHEMBL9208702 0.94 FAAH (0.45) FAAHTRPV1SOAT1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199974-A1 Zinc Free Lubricating Compositions And Methods Of Using The Same THE LUBRIZOL CORPORATION (US) 2024-06-20 US disclosed
US-20240150669-A1 THERMALLY STABLE, LOW TRACTION COEFFICIENT LUBRICANT THE LUBRIZOL CORPORATION (US) 2024-05-09 US disclosed
EP-3833727-B1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS LUBRIZOL CORP (US) 2024-04-17 EP disclosed
EP-4314211-A1 ZINC FREE LUBRICATING COMPOSITIONS AND METHODS OF USING THE SAME The Lubrizol Corporation (US) 2024-02-07 EP disclosed
US-20230416632-A1 Composition and Method for Lubricating Automotive Gears, Axles and Bearings THE LUBRIZOL CORPORATION (US) 2023-12-28 US disclosed
EP-4013841-B1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS LUBRIZOL CORP (US) 2023-10-04 EP disclosed
US-11732208-B2 Composition and method for lubricating automotive gears, axles and bearings THE LUBRIZOL CORPORATION 2023-08-22 US disclosed
EP-4013841-A1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS The Lubrizol Corporation (US) 2022-06-22 EP disclosed
US-20210222082-A1 Composition and Method for Lubricating Automotive Gears, Axles and Bearings THE LUBRIZOL CORPORATION (US) 2021-07-22 US disclosed
EP-3833727-A1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS The Lubrizol Corporation (US) 2021-06-16 EP disclosed
WO-2021034553-A1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS THE LUBRIZOL CORPORATION (US) 2021-02-25 WO disclosed
WO-2020033232-A1 COMPOSITION AND METHOD FOR LUBRICATING AUTOMOTIVE GEARS, AXLES AND BEARINGS THE LUBRIZOL CORPORATION (US) 2020-02-13 WO disclosed