SCHEMBL165481

SCHEMBL165481

CN(C)C(=S)SC(C)(C)C#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
LMNA P02545 3/20 0.42
HTT P42858 2/20 0.42
MGLL Q99685 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
FAAH O00519 1/20 0.42
JAK2 O60674 1/20 0.42
BBOX1 O75936 1/20 0.42
TP53 P04637 1/20 0.42
ALDH2 P05091 1/20 0.42
HSP90AA1 P07900 1/20 0.42
CYP3A4 P08684 1/20 0.42
FBP1 P09467 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
LOX P28300 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12892657 0.76 ALDH1A1 (0.48) ALDH1A1LMNAHTTMGLLTP53
SCHEMBL9641673 0.74 ALDH1A1 (0.50) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL17016738 0.72
SCHEMBL20182723 0.72
SCHEMBL28706133 0.71
SCHEMBL2741384 0.69 FAAH (0.39) MGLLKDM4EFAAHMAPTKMT2A
SCHEMBL1697584 0.68
Thiram SCHEMBL28493531 0.67 ALDH1A1 (0.72) ALDH1A1LMNAHTTMGLLKDM4E
SCHEMBL728486 0.67
SCHEMBL31694218 0.67 ALDH1A1 (0.48) ALDH1A1LMNAHTTMGLLKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747339-A1 INDUSTRIAL GEAR LUBRICANT The Lubrizol Corporation (US) 2026-05-27 EP disclosed
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition DENKA COMPANY LIMITED (JP) 2026-05-12 US disclosed
US-12492279-B2 Chloroprene-based block copolymer, latex, latex composition, and rubber composition DENKA COMPANY LIMITED (JP) 2025-12-09 US disclosed
EP-2292668-B2 Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2025-09-10 EP disclosed
US-20250269096-A1 FLUOROPOLYMER MEDICAL DEVICES UNOMEDICAL AS (DK) 2025-08-28 US disclosed
EP-4282889-B1 (METH)ACRYLIC BLOCK COPOLYMER, (METH)ACRYLIC BLOCK COPOLYMER LATEX, (METH)ACRYLIC BLOCK COPOLYMER LATEX COMPOSITION, AND SHAPED OBJECT DENKA COMPANY LTD (JP) 2025-08-20 EP disclosed
EP-4583934-A1 MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
EP-4583933-A1 FLUOROPOLYMER MEDICAL DEVICES Unomedical A/S (DK) 2025-07-16 EP disclosed
US-20250195832-A1 MEDICAL DEVICES UNOMEDICAL AS (DK) 2025-06-19 US disclosed
US-12312433-B2 Chloroprene-based block copolymer, latex, latex composition, and rubber composition DENKA COMPANY LIMITED (JP) 2025-05-27 US disclosed
US-7205368-B2 S-(α, α′-disubstituted-α′ ′-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom NOVEON, INC. (US) 2007-04-17 US disclosed
EP-1054906-B1 POLYMERIZATION PROCESS WITH LIVING CHARACTERISTICS AND POLYMERS MADE THEREFROM DU PONT (US) 2006-11-22 EP disclosed
WO-2006047398-A2 STAR POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
WO-2006047393-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
WO-2006002496-A1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIVERSITEIT GENT (BE) 2006-01-12 WO disclosed
US-6747111-B2 POLYMERS HAVING LOW POLLYDISPERSITY AND PREDICTABLE SPECIFIC POLYMER ARCHITECTURE AND MOLECULAR WEIGHT ARE PRODUCED BY THE PROCESS. THE POLYMERS PRODUCED BY THE PROCESS ARE SUITABLE FOR USE AS BINDERS IN AUTOMOTIVE OEM AND REFINISH COATINGS. E. I. DU PONT DE NEMOURS AND COMPANY 2004-06-08 US disclosed
US-20040024132-A1 Polymerization process with living characteristics and polymers made therefrom COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-02-05 US disclosed
US-6642318-B1 Sulfur based chain transfer agents; widely compatible; free radical polymerization; producing low polydispersity and predictably specific architecture E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-04 US disclosed
EP-1054906-A1 POLYMERIZATION PROCESS WITH LIVING CHARACTERISTICS AND POLYMERS MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-11-29 EP disclosed
WO-1999031144-A1 POLYMERIZATION PROCESS WITH LIVING CHARACTERISTICS AND POLYMERS MADE THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624196-B2 Rubber composition, vulcanized object obtained from said rubber composition, and vulcanized molded object obtained from said rubber composition ALG3, VCL, DNMT1 ALDH1A1 2251/4885LMNA 1347/4885HTT 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.