Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16540245 | 0.99 | FFAR1 (0.36) | FFAR1FFAR4CTSAPTGESBCL2L1 | |
| SCHEMBL18215371 | 0.93 | PTGES (0.37) | FFAR1FFAR4CTSAPTGESBCL2L1 | |
| SCHEMBL17945642 | 0.93 | PTGES (0.37) | FFAR1FFAR4CTSAPTGESBCL2L1 | |
| Hydrochloric Acid SCHEMBL16540271 | 0.92 | PTGES (0.37) | FFAR1FFAR4CTSAPTGESBCL2L1 | |
| SCHEMBL17939843 | 0.90 | TACR3 (0.32) | CTSAADRB1ADRB3TACR3PPARG | |
| SCHEMBL16548247 | 0.90 | TACR3 (0.32) | CTSAADRB1ADRB3TACR3PPARG | |
| SCHEMBL16548235 | 0.90 | CASR (0.39) | FFAR1TACR3 | |
| SCHEMBL18215373 | 0.89 | PTGS2 (0.40) | FFAR1FFAR4BCL2L1PTGER1PTGER4 | |
| Hydrochloric Acid SCHEMBL17939882 | 0.89 | CASR (0.39) | FFAR1 | |
| SCHEMBL17945975 | 0.89 | PTGS2 (0.40) | FFAR1FFAR4BCL2L1PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |
| US-9493396-B2 | Substituted naphthalene compounds as calcium sensing receptor modulators | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-11-15 | — | — | US | disclosed |
| WO-2015028938-A1 | SUBSTITUTED NAPHTHALENE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2015-03-05 | — | — | WO | disclosed |