Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17831015 | 0.77 | GRM5 (0.34) | SMN1; SMN2GFER | |
| SCHEMBL25518198 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL14682691 | 0.73 | GFER (0.35) | LMNASMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL21074240 | 0.73 | TSHR (0.33) | LMNASMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL21074282 | 0.72 | ALDH1A1 (0.39) | LMNASMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL19999700 | 0.72 | ALDH1A1 (0.39) | LMNASMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL14682692 | 0.71 | HSD11B1 (0.39) | LMNASMN1; SMN2MAPTNOTUM | |
| SCHEMBL19749036 | 0.69 | ALDH1A1 (0.42) | LMNASMN1; SMN2GFERKDM4EMAPT | |
| SCHEMBL19224778 | 0.67 | ALDH1A1 (0.35) | LMNASMN1; SMN2KDM4EMAPTNPSR1 | |
| SCHEMBL15631672 | 0.67 | ALDH1A1 (0.35) | LMNASMN1; SMN2KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9853229-B2 | Organic electroluminescent materials and devices | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2017-12-26 | — | — | US | disclosed |
| US-20150060795-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2015-03-05 | — | — | US | disclosed |