Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551972 | 0.89 | KDM4A (0.40) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL16551911 | 0.82 | CA12 (0.42) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL16551977 | 0.82 | L3MBTL1 (0.36) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL16551914 | 0.80 | KDM4A (0.36) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL16552124 | 0.80 | NPSR1 (0.40) | L3MBTL1MAPTRECQLNPSR1POLB | |
| SCHEMBL16552190 | 0.78 | KDM4A (0.39) | L3MBTL1KDM4AHTTATRKDM4E | |
| SCHEMBL20833996 | 0.78 | CKS1B (0.32) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL18099416 | 0.77 | L3MBTL1 (0.53) | L3MBTL1MAPTNPSR1KDM4ELMNA | |
| SCHEMBL5270836 | 0.77 | ATR (0.51) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL16551880 | 0.77 | MAPT (0.39) | L3MBTL1HTTMAPTRECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042913-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Hangzhou Guanyu Bio-Medical Co., Ltd (CN) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015027959-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海冠宇生物医药科技有限公司 (CN) | 2015-03-05 | — | — | WO | disclosed |