Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551968 | 0.91 | GRM2 (0.39) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL16551952 | 0.86 | KDM4A (0.34) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL17922690 | 0.83 | KDM4A (0.38) | CA1CA2CA9CA12KDM4A | |
| SCHEMBL16552136 | 0.80 | GRM2 (0.43) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL16552148 | 0.79 | GRM2 (0.35) | GRM2KDM4ACACNA1HCACNA1BCACNA1C | |
| SCHEMBL16552112 | 0.79 | L3MBTL1 (0.37) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL16552147 | 0.79 | GRM2 (0.41) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL16552146 | 0.78 | PDE5A (0.41) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL16551961 | 0.76 | KDM4A (0.36) | GRM2CA1CA2CA9CA12 | |
| SCHEMBL20834059 | 0.74 | ABCB1 (0.41) | GRM2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042913-B1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | HANGZHOU GUANYU BIO MEDICAL CO LTD (CN) | 2019-03-20 | — | — | EP | disclosed |
| EP-3042913-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Hangzhou Guanyu Bio-Medical Co., Ltd (CN) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015027959-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海冠宇生物医药科技有限公司 (CN) | 2015-03-05 | — | — | WO | disclosed |