Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551922 | 0.91 | KDM4A (0.38) | GRM2KDM4AL3MBTL1TRPV3ADORA2A | |
| SCHEMBL20833936 | 0.88 | KDM4E (0.36) | GRM2KDM4AL3MBTL1TRPV3NAMPT | |
| SCHEMBL16552171 | 0.86 | KDM4A (0.34) | GRM2KDM4AL3MBTL1PRMT5WDR77 | |
| SCHEMBL16552112 | 0.81 | L3MBTL1 (0.37) | GRM2KDM4AL3MBTL1NAMPTCYP1A2 | |
| SCHEMBL16551995 | 0.81 | KDM4A (0.41) | GRM2KDM4AL3MBTL1TRPV3ADORA2A | |
| SCHEMBL17922690 | 0.81 | KDM4A (0.38) | KDM4AL3MBTL1ADORA2ANAMPTCYP1A2 | |
| SCHEMBL16551996 | 0.80 | KDM4A (0.41) | GRM2KDM4AL3MBTL1TRPV3PRMT5 | |
| SCHEMBL16551990 | 0.79 | GRM2 (0.37) | GRM2KDM4AL3MBTL1NAMPTCACNA1H | |
| SCHEMBL16552014 | 0.78 | PDE5A (0.39) | GRM2KDM4AL3MBTL1TRPV3KCNA5 | |
| SCHEMBL16552097 | 0.76 | KDM4A (0.36) | GRM2KDM4AL3MBTL1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042913-B1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | HANGZHOU GUANYU BIO MEDICAL CO LTD (CN) | 2019-03-20 | — | — | EP | disclosed |
| EP-3042913-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Hangzhou Guanyu Bio-Medical Co., Ltd (CN) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015027959-A1 | CYCLIC PEPTIDE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海冠宇生物医药科技有限公司 (CN) | 2015-03-05 | — | — | WO | disclosed |