Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749257 | 1.00 | MEN1 (0.46) | MEN1KMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL29052481 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPK1S1PR3S1PR1 | |
| SCHEMBL30499570 | 0.82 | MEN1 (0.54) | MEN1KMT2AMAPK1S1PR3S1PR1 | |
| SCHEMBL9948150 | 0.82 | MEN1 (0.54) | MEN1KMT2AMAPK1S1PR3S1PR1 | |
| SCHEMBL19371259 | 0.81 | KMT2A (0.64) | MEN1KMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL16540985 | 0.81 | PLAU (0.36) | GAAMAPK1S1PR3S1PR1KDM4E | |
| SCHEMBL25295115 | 0.81 | GAA (0.43) | MEN1KMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL30484114 | 0.81 | GAA (0.43) | MEN1KMT2AGAASMN1; SMN2MAPK1 | |
| SCHEMBL14321742 | 0.80 | MEN1 (0.44) | MEN1KMT2AMAPK1S1PR3S1PR1 | |
| SCHEMBL19371268 | 0.77 | KMT2A (0.46) | MEN1KMT2AGAASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174674-A1 | NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | APPLIED PHARMACEUTICAL SCIENCE, INC. (CN) | 2024-05-30 | — | — | US | disclosed |
| CN-114907338-B | Nitrogen-containing polycyclic condensed ring compound, pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-4289428-A1 | NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Applied Pharmaceutical Science, Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-4289428-A1 | NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | Applied Pharmaceutical Science, Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |
| CN-114907338-A | Nitrogen-containing polycyclic fused ring compound, and pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| WO-2022166642-A1 | NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 北京志健金瑞生物医药科技有限公司 | 2022-08-11 | — | — | WO | disclosed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9776967-B2 | Carboxamide derivatives as pesticidal compounds | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| EP-3039018-B1 | PYRIDYL CARBOXAMIDE DERIVATIVES WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160309717-A1 | Compounds with Nematicidal Activity | BAYER CROPSCIENCE AG (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2016-08-04 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| WO-2015091424-A1 | COMPOUNDS WITH NEMATICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015055535-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015028427-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AG (DE) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160309717-A1 | Compounds with Nematicidal Activity | ACHE, NAAA, TUBA3C | MEN1 4336/4885KMT2A 1155/4885GAA 1983/4885 |
| US-20160221950-A1 | CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS | ACHE, DDT, NIT2 | MEN1 2640/4885KMT2A 836/4885GAA 1800/4885 |
| US-20240174674-A1 | NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | RET, WEE1, JAK2 | MEN1 211/4885KMT2A 2971/4885GAA 3924/4885 |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | ACHE, DDT, CAT | MEN1 2432/4885KMT2A 3533/4885GAA 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.