Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554424 | 0.93 | MEN1 (0.44) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554440 | 0.93 | MEN1 (0.51) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554310 | 0.93 | KMT2A (0.51) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554480 | 0.93 | MEN1 (0.49) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554423 | 0.92 | MEN1 (0.49) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554522 | 0.91 | MEN1 (0.50) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554488 | 0.89 | RAB9A (0.47) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554555 | 0.88 | RAB9A (0.49) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16554681 | 0.88 | SCN10A (0.50) | KAT6APTGS2 | |
| SCHEMBL16554412 | 0.88 | KAT6A (0.49) | MEN1KMT2AKEAP1NFE2L2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | claimed |
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |