Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554480 | 0.97 | MEN1 (0.49) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554440 | 0.94 | MEN1 (0.51) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554310 | 0.94 | KMT2A (0.51) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554522 | 0.93 | MEN1 (0.50) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554488 | 0.92 | RAB9A (0.47) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554437 | 0.92 | MEN1 (0.48) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554412 | 0.91 | KAT6A (0.49) | MEN1KMT2AKEAP1NFE2L2KAT6A | |
| SCHEMBL16554359 | 0.91 | ALDH1A1 (0.49) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL16554719 | 0.91 | PTGS2 (0.53) | MEN1KMT2APOLBALDH1A1GAA | |
| SCHEMBL16554424 | 0.90 | MEN1 (0.44) | MEN1KMT2AKEAP1NFE2L2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | claimed |
| WO-2015034271-A1 | NOVEL ANTIFUNGAL PYRIDINYLHYDRAZIDE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-03-12 | — | — | WO | disclosed |