SCHEMBL1655538

SCHEMBL1655538

C[Sn](C)(C)c1nc(Cl)nc2c1ncn2Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 9/20 0.64
PNP P00491 1/20 0.51
CNR2 P34972 1/20 0.51
CDK1 P06493 1/20 0.48
PDE4A P27815 2/20 0.47
PDE4B Q07343 2/20 0.47
PDE4C Q08493 2/20 0.47
PDE4D Q08499 2/20 0.47
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12786350 0.82 YTHDC1 (0.69) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL30898278 0.81 YTHDC1 (0.68) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL183057 0.81 YTHDC1 (0.68) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL30586354 0.79 YTHDC1 (0.65) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL2060472 0.79 PDE4A (0.67) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL30586404 0.79 YTHDC1 (0.65) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL27388300 0.78 YTHDC1 (1.00) YTHDC1
SCHEMBL7536448 0.75 YTHDC1 (0.74) YTHDC1CDK1
SCHEMBL17507441 0.74 CNR2 (0.70) YTHDC1PNPCNR2CDK1PDE4A
SCHEMBL22345202 0.73 CNR2 (0.69) YTHDC1PNPCNR2CDK1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488518-A2 HERBICIDAL COMPOUNDS Syngenta Limited (GB) 2012-08-22 EP disclosed
US-20120202690-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (US) 2012-08-09 US disclosed
WO-2011045561-A2 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2011-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202690-A1 HERBICIDAL COMPOUNDS DDT, HAO2, HAAO YTHDC1 3217/4885PNP 1997/4885CNR2 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.