Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556187 | 0.88 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL17092972 | 0.88 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL29728512 | 0.88 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL18050806 | 0.83 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL17113696 | 0.80 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL18050726 | 0.80 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL17113703 | 0.80 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL8910744 | 0.78 | TDP1 (0.52) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL17924112 | 0.78 | L3MBTL1 (0.50) | HSP90AA1HSP90AB1MEN1KMT2ALMNA | |
| SCHEMBL16556110 | 0.78 | EGFR (0.42) | HSP90AA1HSP90AB1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044239-B9 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-08-28 | — | — | EP | disclosed |
| EP-3044239-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-9481745-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-01 | — | — | US | disclosed |
| US-20160208027-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE ITALIA S.R.L. (IT) | 2016-07-21 | — | — | US | disclosed |
| EP-3044239-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015032939-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-03-12 | — | — | WO | disclosed |