Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15269462 | 0.82 | MAPT (0.60) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL29551930 | 0.82 | APEX1 (0.50) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL187016 | 0.82 | KDM4E (0.47) | ALDH1A1HSD17B10HPGDCYP2C19KMT2A | |
| SCHEMBL10477729 | 0.81 | ALDH1A1 (0.47) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| Butane SCHEMBL20514296 | 0.79 | CYP2C19 (0.48) | TDP1ALDH1A1ALOX15CA1CA2 | |
| SCHEMBL6015487 | 0.79 | ALDH1A1 (0.61) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| Biphenyl SCHEMBL20514294 | 0.78 | RXRA (0.46) | TDP1CA1CA2CA9CYP2C19 | |
| SCHEMBL16556201 | 0.78 | HSP90AA1 (0.55) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL420149 | 0.77 | ALDH1A1 (0.59) | TDP1ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL30135395 | 0.77 | ALDH1A1 (0.59) | TDP1ALDH1A1HSD17B10HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681669-A | ORGANIC SOLVENT CONTAINING AN AROMATIC CARBONATE AND DISSOLVED LITHIUM SALT | UBE INDUSTRIES, LTD. (JP) | 1997-10-28 | — | — | US | disclosed |