Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16237078 | 0.92 | SLC6A3 (0.55) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16556133 | 0.89 | HSD17B10 (0.54) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16556052 | 0.88 | KMT2A (0.55) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16965616 | 0.88 | HSD17B10 (0.70) | HSD17B10KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29728640 | 0.88 | HSD17B10 (0.70) | HSD17B10KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL16236627 | 0.87 | HSD17B10 (0.49) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16556191 | 0.87 | HSD17B10 (0.51) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT | |
| SCHEMBL16556275 | 0.86 | TRPV1 (0.50) | HSD17B10KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL16555777 | 0.84 | KDM4E (0.52) | HSD17B10KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL17924112 | 0.84 | L3MBTL1 (0.50) | HSD17B10SLC6A3KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044239-B9 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-08-28 | — | — | EP | disclosed |
| EP-3044239-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-9481745-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-01 | — | — | US | disclosed |
| US-20160208027-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE ITALIA S.R.L. (IT) | 2016-07-21 | — | — | US | disclosed |
| EP-3044239-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015032939-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-03-12 | — | — | WO | disclosed |