Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16557000 | 0.93 | PDE10A (0.34) | GPBAR1CYSLTR1PDE10AALOX5 | |
| SCHEMBL16557009 | 0.85 | TERT (0.35) | GPBAR1CYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL14930063 | 0.84 | CYP1A2 (0.40) | GPBAR1CYSLTR1PDE10A | |
| SCHEMBL12516193 | 0.81 | CCR1 (0.47) | GPBAR1CYSLTR1PDE10A | |
| SCHEMBL12517318 | 0.77 | PDE10A (0.35) | GPBAR1CYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL14925219 | 0.77 | PDE10A (0.40) | GPBAR1CYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL16557004 | 0.76 | PDE10A (0.33) | PDE10A | |
| SCHEMBL2223356 | 0.74 | PDE10A (0.33) | GPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL14925246 | 0.73 | PDE10A (0.37) | GPBAR1CYSLTR1CYSLTR2PDE10AALOX5 | |
| SCHEMBL12517340 | 0.72 | CCR1 (0.48) | GPBAR1CYSLTR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523937-B1 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NAT RECH SCIENT (FR) | 2015-03-11 | — | — | EP | disclosed |