Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16557000 | 0.93 | PDE10A (0.34) | PDE10ACYSLTR1GPBAR1ALOX5CYP1A2 | |
| SCHEMBL14930063 | 0.87 | CYP1A2 (0.40) | TERTPDE10AAPPCYSLTR1GPBAR1 | |
| SCHEMBL16557013 | 0.85 | GPBAR1 (0.37) | PDE10ACYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL16557004 | 0.79 | PDE10A (0.33) | PDE10ACYP1A2 | |
| SCHEMBL12517340 | 0.74 | CCR1 (0.48) | TERTPDE10AAPPCYSLTR1GPBAR1 | |
| SCHEMBL12517339 | 0.74 | PDE10A (0.41) | TERTPDE10ACYSLTR1GPBAR1ALOX5 | |
| SCHEMBL12516490 | 0.71 | TERT (0.50) | TERTPDE10AAPPCYSLTR1GPBAR1 | |
| SCHEMBL16601918 | 0.71 | TERT (0.43) | TERTPDE10AAPPCYSLTR1GPBAR1 | |
| SCHEMBL14925257 | 0.69 | PDE10A (0.38) | TERTPDE10ACYSLTR1GPBAR1ALOX5 | |
| SCHEMBL30824506 | 0.68 | CYSLTR1 (0.62) | PDE10ACYSLTR1GPBAR1CYP1A2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523937-B1 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NAT RECH SCIENT (FR) | 2015-03-11 | — | — | EP | disclosed |