Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | XBP1 | P17861 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655903 | 1.00 | MEN1 (0.55) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL17250086 | 0.88 | MEN1 (0.40) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL13446762 | 0.84 | KMT2A (0.56) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL12012033 | 0.83 | KMT2A (0.57) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1658644 | 0.83 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1658645 | 0.83 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL14404492 | 0.82 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL7018706 | 0.82 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL14867812 | 0.81 | KMT2A (0.74) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1715260 | 0.81 | HRH2 (0.42) | MEN1KMT2ALMNAHTTMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-9018396-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2015-04-28 | — | — | US | disclosed |
| EP-1322710-B2 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | LIFE TECHNOLOGIES CORP (US) | 2015-02-18 | — | — | EP | disclosed |
| US-8614302-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-12-24 | — | — | US | disclosed |
| US-8569506-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-10-29 | — | — | US | disclosed |
| EP-2325263-B1 | Modified carbocyanine dyes and their conjugates | LIFE TECHNOLOGIES CORP (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| EP-1770129-A2 | Modified carbocyanine dyes and their conjugates | Molecular Probes, Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1322710-B1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES INC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-05-11 | — | — | US | disclosed |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-01-05 | — | — | US | disclosed |
| US-6977305-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-6974873-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| EP-1322710-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Molecular Probes Inc. (US) | 2003-07-02 | — | — | EP | disclosed |
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-06-20 | — | — | US | disclosed |
| US-20020064794-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-05-30 | — | — | US | disclosed |
| WO-2002026891-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES, INC. (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | CBR3, IK, CYBA | MEN1 1030/4885KMT2A 3170/4885LMNA 2094/4885 |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | MEN1 1243/4885KMT2A 2895/4885LMNA 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.