Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658645 | 1.00 | PTPN1 (0.41) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL14404492 | 0.99 | PTPN1 (0.41) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL7018706 | 0.99 | PTPN1 (0.41) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL13567272 | 0.94 | MEN1 (0.43) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL1656266 | 0.94 | MEN1 (0.43) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL3901072 | 0.93 | MEN1 (0.42) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL3901077 | 0.93 | MEN1 (0.42) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL3901075 | 0.93 | MEN1 (0.42) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL1715260 | 0.91 | HRH2 (0.42) | PTPN1CHRM1CHRM3OPRK1HRH3 | |
| SCHEMBL1715259 | 0.91 | HRH2 (0.42) | PTPN1CHRM1CHRM3OPRK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-9018396-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2015-04-28 | — | — | US | disclosed |
| EP-1322710-B2 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | LIFE TECHNOLOGIES CORP (US) | 2015-02-18 | — | — | EP | disclosed |
| US-8614302-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-12-24 | — | — | US | disclosed |
| US-8569506-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-10-29 | — | — | US | disclosed |
| EP-2325263-B1 | Modified carbocyanine dyes and their conjugates | LIFE TECHNOLOGIES CORP (US) | 2013-01-23 | — | — | EP | disclosed |
| EP-1322710-B9 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES INC (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1801165-A2 | Modified carbocyanine dyes and their conjugates | Molecular Probes, Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1770129-A2 | Modified carbocyanine dyes and their conjugates | Molecular Probes, Inc. (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1322710-B1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | MOLECULAR PROBES INC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-05-11 | — | — | US | disclosed |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2006-01-05 | — | — | US | disclosed |
| US-6977305-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-6974873-B2 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-06-20 | — | — | US | disclosed |
| US-20020064794-A1 | Modified carbocyanine dyes and their conjugates | MOLECULAR PROBES, INC. | 2002-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077487-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | PTPN1 2599/4885CHRM1 309/4885CHRM3 158/4885 |
| US-20160356681-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | PTPN1 2599/4885CHRM1 309/4885CHRM3 158/4885 |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | PTPN1 2599/4885CHRM1 309/4885CHRM3 158/4885 |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | PTPN1 2599/4885CHRM1 309/4885CHRM3 158/4885 |
| US-20060004188-A1 | Intermediates and the synthesis of modified carbocyanine dyes and their conjugates | CBR3, IK, CYBA | PTPN1 3667/4885CHRM1 716/4885CHRM3 512/4885 |
| US-20060099638-A1 | Modified carbocyanine dyes and their conjugates | IK, CBR3, DRD5 | PTPN1 2599/4885CHRM1 309/4885CHRM3 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.