Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559833 | 0.91 | TDP1 (0.40) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL16559839 | 0.90 | ELANE (0.40) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL16559838 | 0.90 | POLB (0.44) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL24440871 | 0.89 | POLB (0.43) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL18308842 | 0.88 | BACE1 (0.39) | TDP1KMT2AATMELANEGAA | |
| SCHEMBL19158258 | 0.87 | KMT2A (0.37) | TDP1KMT2AATMELANECYP11B1 | |
| SCHEMBL18808109 | 0.87 | HTT (0.40) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL16559829 | 0.87 | POLB (0.47) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL24440804 | 0.86 | POLB (0.41) | TDP1POLBAPEX1HTTKMT2A | |
| SCHEMBL25936691 | 0.86 | HTT (0.41) | TDP1POLBAPEX1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| US-9487702-B2 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| US-9487702-B2 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| EP-2848676-A2 | Liquid crystal medium | Merck Patent GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |
| US-20150070609-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20150070609-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2015-03-12 | — | — | US | disclosed |