Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559832 | 0.87 | TDP1 (0.38) | KMT2AATMELANEGAATDP1 | |
| SCHEMBL19159458 | 0.86 | BACE1 (0.38) | KMT2AATMELANEGAATDP1 | |
| SCHEMBL19159162 | 0.84 | CHEK2 (0.42) | KMT2AATMELANETDP1CHEK2 | |
| SCHEMBL18308842 | 0.81 | BACE1 (0.39) | KMT2AATMELANEGAATDP1 | |
| SCHEMBL16559838 | 0.81 | POLB (0.44) | KMT2AATMELANETDP1CHEK2 | |
| SCHEMBL16559839 | 0.81 | ELANE (0.40) | KMT2AATMELANEGAATDP1 | |
| SCHEMBL19159052 | 0.80 | POLB (0.46) | KMT2AATMELANEGAATDP1 | |
| SCHEMBL22459581 | 0.80 | BACE1 (0.43) | KMT2AATMELANEBACE1EGFR | |
| SCHEMBL21254298 | 0.80 | POLB (0.41) | KMT2AATMELANETDP1CHEK2 | |
| SCHEMBL21400897 | 0.80 | KMT2A (0.44) | KMT2AATMELANEBACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |