Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18808109 | 0.94 | HTT (0.40) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL16559838 | 0.91 | POLB (0.44) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL24440871 | 0.90 | POLB (0.43) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL21891667 | 0.89 | TDP1 (0.41) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL16559829 | 0.88 | POLB (0.47) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL21693389 | 0.86 | POLB (0.40) | HTTTDP1POLBAPEX1ESR1 | |
| SCHEMBL16559832 | 0.86 | TDP1 (0.38) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL22023580 | 0.86 | POLB (0.37) | HTTTDP1POLBAPEX1THRB | |
| SCHEMBL19624269 | 0.86 | HTT (0.42) | HTTTDP1POLBAPEX1KMT2A | |
| SCHEMBL16573122 | 0.85 | POLB (0.49) | HTTTDP1POLBAPEX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056667-B1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-02 | — | — | EP | disclosed |