Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.85 |
| ▸ | FPR2 | P25090 | 5/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562076 | 0.93 | FPR2 (0.73) | CNR1FPR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16562291 | 0.92 | CNR1 (1.00) | CNR1FPR2HTTEPHX2NPC1 | |
| SCHEMBL16562203 | 0.86 | CNR1 (0.63) | CNR1FPR2EPHX2NPC1RAB9A | |
| SCHEMBL16562079 | 0.85 | FPR2 (0.86) | CNR1FPR2HTTNPC1RAB9A | |
| SCHEMBL16562239 | 0.84 | SMN1; SMN2 (0.77) | CNR1FPR2HTTEPHX2NPC1 | |
| SCHEMBL12335330 | 0.84 | CNR1 (0.67) | CNR1FPR2EPHX2NPC1RAB9A | |
| SCHEMBL22834239 | 0.82 | CNR1 (1.00) | CNR1HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20708118 | 0.82 | SMN1; SMN2 (0.68) | CNR1FPR2HTTNPC1RAB9A | |
| SCHEMBL10643851 | 0.82 | LMNA (0.69) | CNR1FPR2HTTSMN1; SMN2 | |
| SCHEMBL17916742 | 0.82 | KMT2A (0.70) | CNR1FPR2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789096-B2 | Methods and compositions for selective and targeted cancer therapy | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-10-17 | — | — | US | disclosed |
| US-9789096-B2 | Methods and compositions for selective and targeted cancer therapy | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160200695-A1 | Methods and Compositions for Selective and Targeted Cancer Therapy | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160200695-A1 | Methods and Compositions for Selective and Targeted Cancer Therapy | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-07-14 | — | — | US | disclosed |
| WO-2015035051-A1 | METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200695-A1 | Methods and Compositions for Selective and Targeted Cancer Therapy | NCOA4, SREBF1, ACOX1 | CNR1 1450/4885FPR2 2631/4885HTT 4435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.