Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | IGLV6-57 | P01721 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457083 | 0.86 | IGLV6-57 (0.56) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL3901017 | 0.85 | ALDH1A1 (0.71) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL1305911 | 0.84 | ALDH1A1 (0.70) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL29558719 | 0.84 | ALDH1A1 (0.70) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL24983388 | 0.84 | HSD17B3 (0.59) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL6688161 | 0.84 | ALDH1A1 (0.64) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL16563064 | 0.84 | IGLV6-57 (0.72) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL29716530 | 0.81 | KDM4E (0.49) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL16563262 | 0.81 | IGLV6-57 (0.54) | ALDH1A1IGLV6-57MEN1MAPTKMT2A | |
| SCHEMBL28347890 | 0.81 | ALDH1A1 (0.57) | ALDH1A1IGLV6-57MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848696-A1 | Caspase-1 imaging probes | Sanofi-Aventis Deutschland GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |
| EP-2848696-A1 | Caspase-1 imaging probes | Sanofi-Aventis Deutschland GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |