Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | GLA | P06280 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573497 | 0.86 | IGLV6-57 (0.47) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL16563325 | 0.86 | IGLV6-57 (0.47) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL16563064 | 0.86 | IGLV6-57 (0.72) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL5964558 | 0.84 | ALDH1A1 (0.72) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL3901017 | 0.82 | ALDH1A1 (0.71) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL6688557 | 0.81 | IGLV6-57 (0.76) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL16563181 | 0.81 | ALDH1A1 (0.51) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL21457083 | 0.78 | IGLV6-57 (0.56) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL1395286 | 0.77 | IGLV6-57 (0.51) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 | |
| SCHEMBL8122108 | 0.77 | ALDH1A1 (0.75) | IGLV6-57ALDH1A1GLAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848696-A1 | Caspase-1 imaging probes | Sanofi-Aventis Deutschland GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |
| EP-2848696-A1 | Caspase-1 imaging probes | Sanofi-Aventis Deutschland GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |