Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.63 |
| ▸ | AR | P10275 | 11/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564562 | 1.00 | PGR (0.63) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL3761697 | 0.89 | PGR (0.64) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL3763162 | 0.89 | PGR (0.64) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564394 | 0.88 | PGR (0.53) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564406 | 0.88 | PGR (0.53) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL13556648 | 0.85 | PGR (0.64) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564584 | 0.85 | PGR (0.46) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564393 | 0.84 | PGR (0.58) | PGRARCYP19A1LMNACYP3A4 | |
| SCHEMBL16564599 | 0.82 | PGR (0.60) | PGRARLMNACYP3A4TSHR | |
| SCHEMBL16564466 | 0.81 | PGR (0.41) | PGRARCYP19A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238149-B1 | 19-NOR-STEROID DERIVATIVES WITH A 15ALPHA, 16ALPHA-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | disclosed |