Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037816 | 0.84 | HPGD (0.38) | HPGDHTTKMT2AALDH1A1NPC1 | |
| SCHEMBL4036448 | 0.82 | HPGD (0.43) | HPGDHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL4036682 | 0.72 | METAP2 (0.44) | HPGDHTTALDH1A1L3MBTL1 | |
| SCHEMBL4040091 | 0.71 | LMNA (0.40) | HPGDKMT2AMEN1LMNA | |
| SCHEMBL4038175 | 0.70 | METAP2 (0.37) | HPGDALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL4039555 | 0.70 | USP2 (0.38) | KMT2AALDH1A1USP2MEN1LMNA | |
| SCHEMBL4034357 | 0.68 | HPGD (0.43) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4037895 | 0.68 | HPGD (0.43) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4039856 | 0.65 | HPGD (0.44) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| Methylmalonic Acid SCHEMBL27707751 | 0.65 | KMT2A (0.53) | HPGDHTTKMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3043865-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015036442-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF HEPATITIS B VIRUS INFECTION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2015-03-19 | — | — | WO | disclosed |