Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 7/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421298 | 1.00 | GSK3B (0.49) | GSK3BKDM1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1421297 | 1.00 | GSK3B (0.49) | GSK3BKDM1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28526332 | 0.87 | PARP1 (0.45) | GSK3BKDM1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28526334 | 0.87 | PARP1 (0.45) | GSK3BKDM1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1305251 | 0.85 | GSK3B (0.49) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A | |
| Benzamidoxime SCHEMBL3715593 | 0.85 | POLB (0.57) | KDM1AGRIN1GRIN2BTSHRPOLB | |
| Benzamidoxime SCHEMBL3715592 | 0.85 | POLB (0.57) | KDM1AGRIN1GRIN2BTSHRPOLB | |
| SCHEMBL1160894 | 0.78 | NOS3 (0.50) | GSK3BKDM1APOLB | |
| SCHEMBL4947766 | 0.78 | NOS3 (0.50) | GSK3BKDM1APOLB | |
| SCHEMBL10761499 | 0.78 | GSK3B (0.53) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004964-A1 | PREPARATION METHOD OF 3-[5-(2-FLUOROPHENYL)-1,2,4-OXADIAZOL-3-YL]BENZOIC ACID | 上海适济生物科技有限公司 | 2017-01-12 | — | — | WO | disclosed |
| US-9481658-B2 | Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound | FUJIFILM CORPORATION (JP) | 2016-11-01 | — | — | US | disclosed |
| US-20150080582-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8981108-B2 | Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound | FUJIFILM CORPORATION (JP) | 2015-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080582-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | PYM1, CCND2, CCNB2 | GSK3B 585/4885KDM1A 2809/4885GRIN2D 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.