Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16572029 | 0.85 | GSK3B (0.49) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1421298 | 0.85 | GSK3B (0.49) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1421297 | 0.85 | GSK3B (0.49) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9608570 | 0.77 | PRSS1 (0.53) | GSK3BPRSS1 | |
| SCHEMBL171168 | 0.77 | GSK3B (0.61) | GSK3BPOLBVNN1GRM5ATIC | |
| SCHEMBL29858580 | 0.77 | GSK3B (0.51) | GSK3BGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2041048 | 0.77 | GSK3B (0.61) | GSK3BPOLBVNN1GRM5ATIC | |
| SCHEMBL1305151 | 0.76 | NOS3 (0.53) | GSK3BENPP2POLBIDO1NOS3 | |
| SCHEMBL4083136 | 0.76 | GSK3B (0.58) | GSK3BENPP2CLK4VNN1GRM5 | |
| Hydrochloric Acid SCHEMBL2869263 | 0.76 | PRSS1 (0.55) | GSK3BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053573-B2 | Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-11-08 | — | — | US | disclosed |
| EP-1751122-B1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | disclosed |
| EP-1751122-A1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | Pierre Fabre Dermo-Cosmetique (FR) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005121108-A1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | POT1, TELO2, CLIC1 | GSK3B 4499/4885GRIN2D 3774/4885GRIN3B 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.