Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12155679 | 0.81 | IL2 (0.47) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12156136 | 0.78 | STIM1 (0.51) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12155503 | 0.77 | RAB9A (0.52) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL16572274 | 0.77 | IL2 (0.47) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL1701867 | 0.77 | RAB9A (0.48) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12155900 | 0.76 | RAB9A (0.56) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12241574 | 0.76 | SMN1; SMN2 (0.47) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12241670 | 0.76 | IL2 (0.47) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL1702582 | 0.75 | STIM1 (0.53) | IL2RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL12155934 | 0.75 | RAB9A (0.48) | IL2RAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980629-B2 | Compounds that modulate intracellular calcium | CALCIMEDICA, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980629-B2 | Compounds that modulate intracellular calcium | CALCIMEDICA, INC. (US) | 2015-03-17 | — | — | US | disclosed |