Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037471 | 0.81 | LMNA (0.43) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL13173383 | 0.81 | LMNA (0.44) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL6032637 | 0.77 | LMNA (0.42) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL16411245 | 0.73 | SMN1; SMN2 (0.38) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL28065328 | 0.72 | — | — | |
| SCHEMBL3289759 | 0.71 | — | — | |
| SCHEMBL3296119 | 0.68 | SMN1; SMN2 (0.46) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL3289898 | 0.67 | SMN1; SMN2 (0.44) | LMNAHPGDPKMMAPTALDH1A1 | |
| SCHEMBL8907250 | 0.66 | — | — | |
| SCHEMBL12611342 | 0.64 | LMNA (0.60) | LMNAHPGDPKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488544-B1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | UNIV MONASH (AU) | 2015-03-18 | — | — | EP | disclosed |