SCHEMBL3289898

SCHEMBL3289898

CCCCCSC1=NCCS1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.44
LMNA P02545 1/20 0.39
ALDH1A1 P00352 6/20 0.39
HPGD P15428 3/20 0.38
MAPT P10636 3/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
PKM P14618 1/20 0.37
GFER P55789 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.36
ALOX12 P18054 1/20 0.36
APOBEC3A P31941 1/20 0.36
KMT2A Q03164 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3290204 0.98 SMN1; SMN2 (0.43) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL16411240 0.98 SMN1; SMN2 (0.43) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL3289890 0.98 SMN1; SMN2 (0.43) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL3296119 0.94 SMN1; SMN2 (0.46) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL11597023 0.89 ALDH1A1 (0.37) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL3289759 0.86
SCHEMBL8906298 0.81 LMNA (0.42) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL8906308 0.81 LMNA (0.42) SMN1; SMN2LMNAALDH1A1HPGDMAPT
SCHEMBL16411237 0.80 SMN1; SMN2 (0.41) SMN1; SMN2LMNAALDH1A1MAPTKMT2A
SCHEMBL8906193 0.78 LMNA (0.44) SMN1; SMN2LMNAALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723440-B2 Functionalized polymers and improved vulcanizates therefrom BRIDGESTONE CORPORATION (JP) 2010-05-25 US claimed
US-20060178467-A1 Tire treads with reduced hysteresis loss BRIDGESTONE CORPORATION (JP) 2006-08-10 US claimed
WO-2018088919-A1 METHOD FOR PRODUCING MODIFIED POLYDIENES, MODIFIED POLYDIENES PRODUCED THEREBY, AND RUBBER MIXTURES BASED ON THE PRODUCED MODIFIED POLYDIENES PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2018-05-17 WO disclosed
US-8207275-B2 Functionalized polymers and improved vulcanizates therefrom BRIDGESTONE CORPORATION (JP) 2012-06-26 US disclosed
US-20100298465-A1 FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM BRIDGESTONE CORPORATION (JP) 2010-11-25 US disclosed
US-7723440-B2 Functionalized polymers and improved vulcanizates therefrom BRIDGESTONE CORPORATION (JP) 2010-05-25 US disclosed
EP-1532179-B1 FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM BRIDGESTONE CORP (JP) 2007-09-19 EP disclosed
US-20060178467-A1 Tire treads with reduced hysteresis loss BRIDGESTONE CORPORATION (JP) 2006-08-10 US disclosed
US-20060074197-A1 Functionalized polymers and improved vulcanizates therefrom BRIDGESTONE CORPORATION (JP) 2006-04-06 US disclosed
EP-1532179-A1 FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM Bridgestone Corporation (JP) 2005-05-25 EP disclosed
WO-2004020475-A1 FUNCTIONALIZED POLYMERS AND IMPROVED VULCANIZATES THEREFROM BRIDGESTONE CORPORATION (JP) 2004-03-11 WO disclosed