Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448447 | 1.00 | KHK (0.69) | KHKSMN1; SMN2ALDH1A1CYP11B2KEAP1 | |
| SCHEMBL29448448 | 1.00 | KHK (0.69) | KHKSMN1; SMN2ALDH1A1CYP11B2KEAP1 | |
| SCHEMBL31633214 | 0.85 | KHK (0.67) | KHKSMN1; SMN2ALDH1A1CYP11B2NPSR1 | |
| SCHEMBL14332441 | 0.85 | KHK (0.67) | KHKSMN1; SMN2ALDH1A1CYP11B2NPSR1 | |
| SCHEMBL566209 | 0.84 | KHK (0.57) | KHKSMN1; SMN2ALDH1A1NPSR1CYP1A2 | |
| SCHEMBL19220966 | 0.83 | KHK (0.65) | KHKSMN1; SMN2ALDH1A1CYP11B2NPSR1 | |
| SCHEMBL23860801 | 0.82 | KHK (0.73) | KHKSMN1; SMN2ALDH1A1CYP11B2KEAP1 | |
| SCHEMBL33526529 | 0.82 | KHK (0.53) | KHKSMN1; SMN2ALDH1A1CYP11B2KEAP1 | |
| SCHEMBL6050497 | 0.82 | KHK (0.62) | KHKSMN1; SMN2ALDH1A1CYP11B2NPSR1 | |
| SCHEMBL9967116 | 0.82 | KHK (1.00) | KHKSMN1; SMN2ALDH1A1CYP11B2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114990898-A | High-elasticity wear-resistant fabric and preparation method thereof | 王正文 | 2022-09-02 | — | — | CN | claimed |
| US-7414136-B2 | Method for producing 3-substituted 2-chloro-5-fluoro-pyridine or its salt | ASAHI GLASS COMPANY, LIMITED (JP) | 2008-08-19 | — | — | US | claimed |
| US-6441182-B1 | Method for the production of 2,6-dichloro-5-fluoro-nicotinic acid and coarse and particularly pure 2,6-dichloro-5-fluoro-nicotinic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | claimed |
| EP-1192138-A1 | METHOD FOR THE PRODUCTION OF 2,6-DICHLORO-5-FLUORO-NICOTINIC ACID AND COARSE AND PARTICULARLY PURE 2,6-DICHLORO-5-FLUORO-NICOTINIC ACID | Bayer Aktiengesellschaft (DE) | 2002-04-03 | — | — | EP | claimed |
| US-6197964-B1 | CHLORINATION USING BASIC CATALYST; DESALTING, HYDROLYSIS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| WO-2000076978-A1 | METHOD FOR THE PRODUCTION OF 2,6-DICHLORO-5-FLUORO-NICOTINIC ACID AND COARSE AND PARTICULARLY PURE 2,6-DICHLORO-5-FLUORO-NICOTINIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | claimed |
| EP-0973745-A1 | METHOD FOR THE PRODUCTION OF 2,6-DICHLORO-5-FLUORONICOTINONITRILE AND THE CHEMICAL COMPOUND 3-CYANO-2-HYDROXY-5-FLUOROPYRIDE-6-ONE-MONOSODIUM SALT AND ITS TAUTOMERS | BAYER AG (DE) | 2000-01-26 | — | — | EP | claimed |
| WO-1998043958-A1 | METHOD FOR THE PRODUCTION OF 2,6-DICHLORO-5-FLUORONICOTINONITRILE AND THE CHEMICAL COMPOUND 3-CYANO-2-HYDROXY-5-FLUOROPYRIDE-6-ONE-MONOSODIUM SALT AND ITS TAUTOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-08 | — | — | WO | claimed |
| EP-0333020-A2 | Process for the preparation of substituted pyridines | ABBOTT LABORATORIES (US) | 1989-09-20 | — | — | EP | claimed |
| JP-1299272-A | — | — | None | — | — | JP | disclosed |
| US-20260138991-A1 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12630549-B2 | Pyrazoleamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-12583852-B2 | Heterocycle derivative | JW PHARMACEUTICAL CORPORATION (KR) | 2026-03-24 | — | — | US | disclosed |
| EP-4705298-A2 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | Moma Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-0132845-B1 | NOVEL 1,8-NAPHTHYRIDINE DERIVATIVES, AND PROCESS FOR PREPARATION THEREOF | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-04-13 | — | — | EP | disclosed |
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4617308-A | 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0187376-A2 | 6,7-Disubstituted 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |
| EP-0160578-A1 | 1,8-Naphthyridine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0132845-A2 | Novel 1,8-Naphthyridine derivatives, and process for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260138991-A1 | SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES | POLA1, SUB1, CTDSP1 | KHK 1388/4885SMN1; SMN2 836/4885ALDH1A1 840/4885 |
| US-12583852-B2 | Heterocycle derivative | AR, SRD5A1, NR5A1 | KHK 3410/4885SMN1; SMN2 4493/4885ALDH1A1 1733/4885 |
| US-12630549-B2 | Pyrazoleamide derivatives | CYP11B2, CYP11B1, ADRA1B | KHK 1298/4885SMN1; SMN2 2210/4885ALDH1A1 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.