SCHEMBL165778

SCHEMBL165778

CC(C)c1cc(C(C)C)c(-c2ccccc2P(C(C)(C)C)C(C)(C)C)c(C(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
FABP3 P05413 2/20 0.32
FABP4 P15090 2/20 0.32
FABP5 Q01469 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353263 1.00 ROCK2 (0.35) ROCK2GABRA1GABRB2FABP3FABP4
SCHEMBL28313352 0.98 ROCK2 (0.34) ROCK2GABRA1GABRB2FABP3FABP4
SCHEMBL19928426 0.94 ROCK2 (0.32) ROCK2
SCHEMBL29912661 0.94 ROCK2 (0.32) ROCK2
SCHEMBL29946397 0.91 FABP3 (0.41) FABP3FABP4FABP5
Acetonitrile SCHEMBL30092421 0.87
Trifluoromethanesulfonic Acid SCHEMBL28465642 0.86 FABP3 (0.38) FABP3FABP4FABP5PDK2
Trifluoromethanesulfonic Acid SCHEMBL28465644 0.86 GPR3 (0.36) FABP3FABP4FABP5
Phenethylamine SCHEMBL21198481 0.86 HTR2A (0.37)
SCHEMBL4003562 0.86 ROCK2 (0.37) ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6033 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146125-A1 LADDER POLYMERS AND IMPROVED METHODS OF MAKING THE SAME OSMOSES INC. (US) 2026-05-28 US claimed
WO-2026086030-A1 METHOD FOR CONSTRUCTING CHIRALITY OF PYRAN RING IN ORFORGLIPRON BY MEANS OF ENZYMATIC CATALYSIS 成都安迈博生物医药有限公司 2026-04-30 WO claimed
US-20260062361-A1 PROCESS FOR THE PREPARATION OF BIO-BASED OLEFINS FROM PRIMARY ALCOHOL BASF SE (DE) 2026-03-05 US claimed
EP-4678632-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2026-01-14 EP claimed
US-20250388564-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS INC (US) 2025-12-25 US claimed
US-20250346557-A1 METHOD FOR PRODUCING ARYL COMPOUND CONTAINING TRITYLSULFANYL GROUP AGC Inc. (JP) 2025-11-13 US claimed
EP-4634171-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE F. Hoffmann-La Roche AG (CH) 2025-10-22 EP claimed
US-20250313551-A1 PROCESS FOR THE PREPARATION OF A QUINAZOLINONE DERIVATIVE HOFFMANN-LA ROCHE INC. (US) 2025-10-09 US claimed
EP-4601774-A1 LADDER POLYMERS AND IMPROVED METHODS OF MAKING THE SAME Osmoses Inc. (US) 2025-08-20 EP claimed
US-20250197380-A1 PHARMACEUTICAL INTERMEDIATE AND SYNTHESIS METHOD, AND ISOQUINOLINE DERIVATIVE AND SYNTHESIS METHOD THEREFOR BANGENTAI(SHANDONG) BIOSCIENCES GROUP SHARE CO., LTD. (CN) 2025-06-19 US claimed
US-20120116109-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-10 US claimed
US-20120014913-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2012-01-19 US claimed
US-20100081805-A1 Preparation of a Quinolinyloxydiphenylcyclopropanedicarboxamide EXELIXIS, INC. 2010-04-01 US claimed
US-7531695-B2 Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders AUSPEX PHARMACEUTICAL, INC (US) 2009-05-12 US claimed
US-20070129392-A1 Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders AUSPEX PHARMACEUTICALS, INC. 2007-06-07 US claimed
US-20070078189-A1 Novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders AUSPEX PHARMACEUTICALS (US) 2007-04-05 US claimed
EP-1636160-A4 NOVEL THERAPEAUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS AUSPEX PHARMACEUTICALS (US) 2006-09-27 EP claimed
EP-1636160-A2 NOVEL THERAPEAUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS Auspex Pharmaceuticals (US) 2006-03-22 EP claimed
WO-2005108338-A1 NOVEL THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS AUSPEX PHARMACEUTICALS (US) 2005-11-17 WO claimed
WO-2005000233-A2 NOVEL THERAPEAUTIC AGENTS FOR THE TREATMENT OF CANCER, METABOLIC DISEASES AND SKIN DISORDERS AUSPEX PHARMACEUTICALS (US) 2005-01-06 WO claimed