SCHEMBL16579451

SCHEMBL16579451

Cc1noc(-c2cccc(-c3noc(-c4cccc(-c5nc(-c6cccc(-c7nc(C)no7)c6)no5)c4)n3)c2)n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 5/20 0.70
MAPT P10636 2/20 0.70
L3MBTL1 Q9Y468 1/20 0.62
RAB9A P51151 9/20 0.58
NPC1 O15118 9/20 0.58
SMN1; SMN2 Q16637 6/20 0.56
KDM4E B2RXH2 3/20 0.56
HSD17B10 Q99714 3/20 0.56
TSHR P16473 3/20 0.56
NFKB1 P19838 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
LMNA P02545 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
THRB P10828 1/20 0.54
GAA P10253 1/20 0.54
NR1H4 Q96RI1 1/20 0.53
ALDH1A1 P00352 2/20 0.51
ACHE P22303 1/20 0.51
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13167092 1.00 TP53 (0.70) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL2619077 0.98 TP53 (0.68) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL2618900 0.96 TP53 (0.70) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13167030 0.95 TP53 (0.73) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13130240 0.94 L3MBTL1 (0.75) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13415310 0.93 TP53 (0.71) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13167413 0.93 TP53 (0.81) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13415304 0.93 TP53 (0.64) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL16579414 0.86 L3MBTL1 (0.86) TP53MAPTL3MBTL1RAB9ANPC1
SCHEMBL13882259 0.86 RAB9A (0.77) TP53MAPTL3MBTL1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9481658-B2 Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
US-20150080582-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND FUJIFILM CORPORATION (JP) 2015-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080582-A1 OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND PYM1, CCND2, CCNB2 TP53 2976/4885MAPT 848/4885L3MBTL1 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.