Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242960 | 1.00 | HDAC1 (0.47) | HDAC1HDAC2MDM4TP53KMT2A | |
| SCHEMBL29594836 | 0.89 | MDM4 (0.50) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL8227141 | 0.89 | MDM4 (0.50) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL29362168 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL31248559 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL29352034 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL118112 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL15521126 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL8227161 | 0.89 | MDM4 (0.54) | MDM4TP53KMT2ACASP3 | |
| SCHEMBL8226910 | 0.87 | MDM4 (0.50) | MDM4TP53KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015036927-A1 | IMMUNOMODULATING PEPTIDOMIMETIC DERIVATIVES | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-03-19 | — | — | WO | disclosed |