SCHEMBL29362168

SCHEMBL29362168

O=C(C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ CASP3 P42574 2/20 0.50
▸ MDM2 Q00987 6/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ TLR2 O60603 2/20 0.46
▸ SLC17A5 Q9NRA2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118112 1.00 MDM4 (0.54) MDM4TP53CASP3MDM2KMT2A
SCHEMBL15521126 1.00 MDM4 (0.54) MDM4TP53CASP3MDM2KMT2A
SCHEMBL31248559 1.00 MDM4 (0.54) MDM4TP53CASP3MDM2KMT2A
SCHEMBL8227161 1.00 MDM4 (0.54) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29352034 1.00 MDM4 (0.54) MDM4TP53CASP3MDM2KMT2A
SCHEMBL20592813 0.94 MDM2 (0.51) MDM4TP53CASP3MDM2KMT2A
SCHEMBL20592811 0.94 MDM2 (0.51) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29759385 0.94 MDM2 (0.51) MDM4TP53CASP3MDM2KMT2A
SCHEMBL29493132 0.92 MDM2 (0.53) MDM4TP53CASP3MDM2TLR2
SCHEMBL8226910 0.92 MDM4 (0.50) MDM4TP53CASP3KMT2ATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041441-A Synthesis method of daptomycin 申联生物医药(上海)股份有限公司 2023-05-02 — — CN claimed
CN-111228508-B Multi-target anti-tumor polypeptide drug conjugate and preparation method and application thereof 暨南大学 2023-02-17 — — CN claimed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 — — US disclosed
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 — — US disclosed
EP-4661891-A2 PEPTIDES FOR TREATING NEUROLOGICAL DISORDERS Creative Bio-Peptides Inc. (US) 2025-12-17 — — EP disclosed
EP-3071702-B1 SYNTHESIS OF L-NUCLEIC ACIDS BY MEANS OF AN ENZYME APTARION BIOTECH AG (DE) 2025-07-16 — — EP disclosed
US-20250195602-A1 Compositions and Methods for Treating Neuropathy CREATIVE BIO-PEPTIDES, INC. 2025-06-19 — — US disclosed
US-20250154197-A1 LIPOLYTIC PEPTIDES FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA (ES) 2025-05-15 — — US disclosed
EP-4547337-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS Sanofi (FR) 2025-05-07 — — EP disclosed
WO-2024003313-A9 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR ANTAGONISTS SANOFI (FR) 2025-03-20 — — WO disclosed
WO-2025051920-A1 NEW PEPTIDES AS SELECTIVE IL-23 RECEPTOR INHIBITORS SANOFI (FR) 2025-03-13 — — WO disclosed
CN-108794422-B Heterocyclic compounds as PD-L1 inhibitors 南京圣和药业股份有限公司 2022-07-01 — — CN disclosed
CN-112500457-B Dual-targeting FOXM1/CDK1 anti-tumor polypeptide 长沙新生康源生物医药有限公司 2022-06-17 — — CN disclosed
CN-108164474-B 1,2,4- diazole derivatives as immunomodulators 奥瑞基尼探索技术有限公司 2022-05-17 — — CN disclosed
WO-2022082312-A1 NOVEL CXCR4-TARGETING COMPOUNDS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-04-28 — — WO disclosed
WO-2022082006-A1 BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS SRI INTERNATIONAL (US) 2022-04-21 — — WO disclosed
WO-2022075974-A1 CYCLIC TREX1 INHIBITORS Venenum Biodesign, LLC (US) 2022-04-14 — — WO disclosed
EP-3966234-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF Consejo Superior De Investigaciones Científicas (ES) 2022-03-16 — — EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
US-20220024882-A1 NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM4 4874/4885TP53 2182/4885CASP3 1790/4885
US-20220024882-A1 NOVEL TUMOR ANTIGEN BINDING AGENTS AND USES THEREOF CD74, MICA, CD2BP2 MDM4 1065/4885TP53 4/4885CASP3 4252/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM4 3817/4885TP53 1733/4885CASP3 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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