Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470672 | 0.76 | HSP90AA1 (0.59) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL16582720 | 0.74 | KDM4E (0.43) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL16582584 | 0.74 | CCR1 (0.37) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL30733943 | 0.73 | HSP90AA1 (0.56) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL17523388 | 0.73 | HSP90AA1 (0.64) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL422507 | 0.73 | HSP90AA1 (0.56) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL15374722 | 0.73 | HSP90AA1 (0.56) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL5473648 | 0.73 | HSP90AA1 (0.62) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL19859927 | 0.71 | CCR1 (0.38) | HSP90AA1L3MBTL1NPC1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27667853 | 0.71 | HSP90AA1 (0.54) | HSP90AA1L3MBTL1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044284-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| WO-2015036074-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160233443-A1 | Metal Complexes | AP1M1, SOD1, AP3M1 | HSP90AA1 4306/4885L3MBTL1 2753/4885NPC1 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.