Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 8/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | LOX | P28300 | 3/20 | 0.45 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107151 | 0.84 | LOXL2 (0.61) | LOXL2LOXLOXL3ADRB2 | |
| Hydrochloric Acid SCHEMBL5013442 | 0.82 | LOXL2 (0.59) | LOXL2LOXLOXL3ADRB2 | |
| SCHEMBL10651314 | 0.82 | LOXL2 (0.46) | LOXL2HRH1LOXLOXL3RECQL | |
| SCHEMBL23706252 | 0.82 | NR3C2 (0.51) | LOXL2HRH1LOXLOXL3TAAR1 | |
| SCHEMBL15200880 | 0.78 | NOS3 (0.61) | LOXL2LOXLOXL3TAAR1KDM4E | |
| SCHEMBL4134209 | 0.78 | NOS3 (0.61) | LOXL2LOXLOXL3TAAR1DRD2 | |
| SCHEMBL2642380 | 0.78 | RECQL (0.55) | LOXL2LOXLOXL3RECQL | |
| SCHEMBL3915085 | 0.77 | LOXL2 (0.50) | LOXL2LOXTAAR1DRD2DRD1 | |
| SCHEMBL16635231 | 0.77 | LOXL2 (0.50) | LOXL2LOXLOXL3TAAR1DRD2 | |
| Hydrochloric Acid SCHEMBL6953232 | 0.77 | NOS3 (0.59) | LOXL2LOXLOXL3TAAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833768-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | IMPOSSIBLE FOODS INC. | 2017-11-09 | — | — | US | disclosed |
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | disclosed |
| US-20150087532-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087532-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | RAB5IF, MRPL21, RPS27A | LOXL2 3343/4885HRH1 3961/4885LOX 2513/4885 |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | RAB5IF, MRPL21, RPS27A | LOXL2 3343/4885HRH1 3961/4885LOX 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.