Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | CTSV | O60911 | 3/20 | 0.56 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15968165 | 0.91 | FOLH1 (0.55) | FOLH1CTSVCTSLMRGPRX4NPC1 | |
| SCHEMBL19667234 | 0.88 | FOLH1 (0.56) | FOLH1CTSVCTSLMRGPRX4NPC1 | |
| SCHEMBL31166843 | 0.88 | MAOB (0.57) | CTSVCTSLMRGPRX4NPC1L3MBTL1 | |
| SCHEMBL25298462 | 0.88 | FOLH1 (0.55) | FOLH1CTSVCTSLMRGPRX4NPC1 | |
| SCHEMBL30442197 | 0.88 | FOLH1 (0.55) | FOLH1CTSVCTSLMRGPRX4NPC1 | |
| SCHEMBL24983867 | 0.87 | FOLH1 (0.65) | FOLH1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL30892473 | 0.87 | FOLH1 (0.65) | FOLH1CTSVCTSLKDM4EALDH1A1 | |
| SCHEMBL10089235 | 0.87 | FOLH1 (0.69) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL20400911 | 0.87 | FOLH1 (0.55) | FOLH1CTSVCTSLMRGPRX4NPC1 | |
| SCHEMBL19679217 | 0.87 | PTGER1 (0.55) | FOLH1CTSVCTSLMRGPRX4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040425-A1 | RESORCINOL N-ARYL AMIDE COMPOUNDS, FOR USE AS PYRUVATE DEHYDROGENASE KINASE INHIBITORS | VERNALIS (R&D) LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |