Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051084 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTMCL1CYP1A2CYP3A4 | |
| SCHEMBL10726725 | 0.77 | MAPT (0.35) | ALDH1A1MAPTPKMKDM4E | |
| SCHEMBL2780499 | 0.75 | ALDH1A1 (0.39) | ALDH1A1PKMKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6775496 | 0.74 | ALDH1A1 (0.38) | ALDH1A1PKMKDM4EL3MBTL1 | |
| SCHEMBL569818 | 0.70 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1900149 | 0.68 | POLB (0.43) | ALDH1A1CYP1A2ATMPOLBL3MBTL1 | |
| SCHEMBL6264012 | 0.68 | POLB (0.43) | ALDH1A1CYP1A2ATMPOLBL3MBTL1 | |
| SCHEMBL4411485 | 0.68 | POLB (0.43) | ALDH1A1CYP1A2ATMPOLBL3MBTL1 | |
| SCHEMBL4411484 | 0.68 | POLB (0.43) | ALDH1A1CYP1A2ATMPOLBL3MBTL1 | |
| SCHEMBL24322196 | 0.68 | MAPT (0.39) | ALDH1A1MAPTHPGDPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-08-25 | — | — | US | claimed |
| EP-3049428-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-08-03 | — | — | EP | claimed |
| WO-2015040235-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-03-26 | — | — | WO | claimed |
| US-10954269-B2 | Anti-inflammatory tripeptides | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20190153029-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2019-05-23 | — | — | US | disclosed |
| US-10227379-B2 | Anti-inflammatory tripeptides | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2019-03-12 | — | — | US | disclosed |
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2016-08-25 | — | — | US | disclosed |
| EP-3049428-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) | 2016-08-03 | — | — | EP | disclosed |
| WO-2015040235-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244484-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | VIP, TNF, ENPEP | ALDH1A1 2456/4885MAPT 3805/4885MCL1 2910/4885 |
| US-20190153029-A1 | ANTI-INFLAMMATORY TRIPEPTIDES | VIP, TNF, ENPEP | ALDH1A1 2456/4885MAPT 3805/4885MCL1 2910/4885 |
| US-10954269-B2 | Anti-inflammatory tripeptides | VIP, TNF, ENPEP | ALDH1A1 2456/4885MAPT 3805/4885MCL1 2910/4885 |
| US-10227379-B2 | Anti-inflammatory tripeptides | VIP, TNF, ENPEP | ALDH1A1 2456/4885MAPT 3805/4885MCL1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.