Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19667650 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL19667724 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL9618188 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL9618184 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL19679881 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL19679880 | 0.77 | PDCD4 (0.42) | CA1CA4CA14CA3CA9 | |
| SCHEMBL981700 | 0.75 | — | — | |
| SCHEMBL2401895 | 0.72 | PDCD4 (0.49) | CA1CA4CA14CA3CA9 | |
| SCHEMBL14496504 | 0.72 | PDCD4 (0.49) | CA1CA4CA14CA3CA9 | |
| SCHEMBL10114797 | 0.71 | PDCD4 (0.38) | CA1CA4CA14CA3CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9999612-B2 | PPARs agonist activity enhancing drug | TSUJIMOTO CHEMICAL CO., LTD. (JP) | 2018-06-19 | — | — | US | disclosed |
| US-20160374986-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | TSUJIMOTO CHEMICAL CO., LTD. (JP) | 2016-12-29 | — | — | US | disclosed |
| US-20160024041-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | TSUJIMOTO CHEMICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| US-20150087846-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | TSUJIMOTO CHEMICAL CO., LTD. (JP) | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087846-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | PPARA, PPARD, PPARG | CA1 3348/4885CA4 2293/4885CA14 3460/4885 |
| US-20160024041-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | PPARA, PPARG, PPARD | CA1 4869/4885CA4 4735/4885CA14 4872/4885 |
| US-20160374986-A1 | PPARs AGONIST ACTIVITY ENHANCING DRUG | PPARA, PPARG, PPARD | CA1 4806/4885CA4 4552/4885CA14 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.