Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA5A | P35218 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10114642 | 0.74 | TUBB4A (0.32) | — | |
| SCHEMBL10097751 | 0.71 | CCR5 (0.39) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL16586262 | 0.71 | CA1 (0.40) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL9618188 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL19667724 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL9618184 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL19679880 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL19667650 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL19679881 | 0.70 | PDCD4 (0.42) | PDCD4CA1CA4CA14CA3 | |
| SCHEMBL11983272 | 0.69 | MTNR1A (0.46) | PDCD4CA1CA4CA14CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404912-A2 | Process and intermediates for the preparation of antitumoral dihydropyran-2-one compounds | Pharma Mar S.A. (ES) | 2012-01-11 | — | — | EP | disclosed |
| EP-2404913-A2 | Process and intermediates for the preparation of antitumoral dihydropyran-2-one compounds | Pharma Mar S.A. (ES) | 2012-01-11 | — | — | EP | disclosed |