SCHEMBL19667650

SCHEMBL19667650

CC/C=C\C[C@@H]1CC=CC(=O)O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD4 Q53EL6 2/20 0.42
CA1 P00915 4/20 0.38
CA4 P22748 4/20 0.38
CA14 Q9ULX7 4/20 0.38
CA3 P07451 1/20 0.38
CA12 O43570 3/20 0.37
CA5A P35218 3/20 0.37
CA9 Q16790 3/20 0.37
CA5B Q9Y2D0 3/20 0.37
CA2 P00918 2/20 0.37
CA7 P43166 1/20 0.37
MEN1 O00255 1/20 0.36
JAK2 O60674 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19679881 1.00 PDCD4 (0.42) PDCD4CA1CA4CA14CA3
SCHEMBL19667724 1.00 PDCD4 (0.42) PDCD4CA1CA4CA14CA3
SCHEMBL19679880 1.00 PDCD4 (0.42) PDCD4CA1CA4CA14CA3
SCHEMBL9618184 1.00 PDCD4 (0.42) PDCD4CA1CA4CA14CA3
SCHEMBL9618188 1.00 PDCD4 (0.42) PDCD4CA1CA4CA14CA3
SCHEMBL981700 0.82
SCHEMBL16586262 0.77 CA1 (0.40) PDCD4CA1CA4CA14CA3
SCHEMBL14496504 0.75 PDCD4 (0.49) PDCD4CA1CA4CA14CA3
SCHEMBL2401895 0.75 PDCD4 (0.49) PDCD4CA1CA4CA14CA3
SCHEMBL3662595 0.72 PDCD4 (0.53) PDCD4CA1CA4CA14CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP claimed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP claimed
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 CN claimed
EP-4444108-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT Symrise AG (DE) 2024-10-16 EP claimed
US-20240245085-A1 FLAVORING COMPOSITIONS FOR TASTE IMPROVEMENT SYMRISE AG (DE) 2024-07-25 US claimed
WO-2024028513-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS SYMRISE AG (DE) 2024-02-08 WO claimed
EP-4161291-B1 FLAVORING COMPOSITIONS FOR TASTE IMPROVEMENT SYMRISE AG (DE) 2023-11-01 EP claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 EP claimed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023104293-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2023-06-15 WO claimed
EP-4161293-A1 FLAVOURING COMPOSITION WITH BALANCED TASTE PROFILE Symrise AG (DE) 2023-04-12 EP claimed
WO-2022258736-A1 FLAVOURING COMPOSITION WITH BALANCED TASTE PROFILE SYMRISE AG (DE) 2022-12-15 WO claimed
WO-2022258161-A1 FLAVOURING COMPOSITION WITH BALANCED TASTE PROFILE SYMRISE AG (DE) 2022-12-15 WO claimed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed
WO-2022106452-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 PDCD4 3204/4885CA1 1227/4885CA4 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.