Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901077 | 1.00 | MEN1 (0.42) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1656266 | 0.99 | MEN1 (0.43) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL13567272 | 0.99 | MEN1 (0.43) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL3901075 | 0.98 | MEN1 (0.42) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1658645 | 0.93 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL1658644 | 0.93 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL14404492 | 0.92 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL7018706 | 0.92 | PTPN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL10111563 | 0.88 | MEN1 (0.52) | MEN1KMT2ALMNAHTTMMP14 | |
| SCHEMBL3825907 | 0.87 | MEN1 (0.41) | MEN1KMT2ALMNAHTTMMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553869-B2 | Protein probe compounds, compositions, and methods | PIERCE BIOTECHNOLOGY, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080026478-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | PIERCE BIOTECHNOLOGY, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| WO-2008013543-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | PIERCE BIOTECHNOLOGY, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080026478-A1 | PROTEIN PROBE COMPOUNDS, COMPOSITIONS, AND METHODS | HIRA, CUTA, MRPS27 | MEN1 460/4885KMT2A 1195/4885LMNA 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.