Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984386 | 0.98 | KDM4E (0.65) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL1687647 | 0.84 | HSD17B10 (0.49) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL14815362 | 0.82 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL17075223 | 0.82 | KDM4E (0.48) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL14815485 | 0.82 | HSD17B10 (0.48) | KDM4EHPGDHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL20091291 | 0.81 | KDM4E (0.47) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL14760387 | 0.80 | KDM4E (0.45) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL12145679 | 0.79 | KDM4E (0.55) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL14815430 | 0.78 | KDM4E (0.46) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL1687637 | 0.78 | KDM4E (0.43) | KDM4EHPGDHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160233444-A1 | POLYCYCLIC PHENYLPYRIDINE IRIDIUM COMPLEXES AND DERIVATIVES THEREOF FOR OLEDS | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| EP-3046927-A1 | POLYCYCLIC PHENYLPYRIDINE IRIDIUM COMPLEXES AND DERIVATIVES THEREOF FOR OLEDS | Merck Patent GmbH (DE) | 2016-07-27 | — | — | EP | disclosed |
| WO-2015039723-A1 | POLYCYCLIC PHENYLPYRIDINE IRIDIUM COMPLEXES AND DERIVATIVES THEREOF FOR OLEDS | MERCK PATENT GMBH (DE) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160233444-A1 | POLYCYCLIC PHENYLPYRIDINE IRIDIUM COMPLEXES AND DERIVATIVES THEREOF FOR OLEDS | OCIAD1, OCIAD2, OPRM1 | KDM4E 4066/4885HPGD 1123/4885HSD17B10 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.