Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752605 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL25752603 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL23563157 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL20613136 | 0.77 | KMT2A (0.38) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL22889680 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7003109 | 0.76 | L3MBTL1 (0.39) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL9804987 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL10660840 | 0.74 | — | — | |
| SCHEMBL20920913 | 0.72 | — | — | |
| SCHEMBL24754894 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987269-B2 | Certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor | HUTCHISON MEDIPHARMA LIMITED (CN) | 2015-03-24 | — | — | US | disclosed |