Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MYC | P01106 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAX | P61244 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409789 | 0.81 | IDO1 (0.74) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16139723 | 0.77 | MYC (0.68) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17546359 | 0.73 | IDO1 (0.40) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15934061 | 0.71 | MEN1 (0.47) | IDO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15966206 | 0.71 | EPAS1 (0.54) | IDO1MEN1KMT2AMYCMAPK1 | |
| SCHEMBL27580181 | 0.70 | EGFR (0.56) | KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10338230 | 0.70 | GAA (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL679008 | 0.70 | MEN1 (0.41) | IDO1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL49571 | 0.68 | RAB9A (0.55) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL15257089 | 0.68 | ELANE (0.37) | IDO1MEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8986650-B2 | Complex folate-NOTA-Ga68 | GUERBET (FR) | 2015-03-24 | — | — | US | disclosed |