Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.74 |
| ▸ | MEN1 | O00255 | 11/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | MYC | P01106 | 7/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MAX | P61244 | 3/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22030234 | 0.85 | MEN1 (0.73) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL300424 | 0.85 | IDO1 (1.00) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2459654 | 0.85 | MEN1 (1.00) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3693038 | 0.85 | IDO1 (0.67) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6834810 | 0.84 | IDO1 (0.78) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL16107923 | 0.83 | MEN1 (0.73) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12040492 | 0.83 | MEN1 (0.67) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6834736 | 0.83 | IDO1 (0.76) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6833753 | 0.83 | IDO1 (0.76) | IDO1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3702011 | 0.83 | IDO1 (0.76) | IDO1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120064003-A1 | COMPLEX FOLATE-NOTA-Ga68 | GUERBET (FR) | 2012-03-15 | — | — | US | disclosed |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229980-A1 | OLIGONUCLEOTIDE PROBE AND USE THEREOF | DCLRE1B, NSUN2, MTX2 | IDO1 3062/4885KMT2A 2287/4885MEN1 2002/4885 |
| US-20120064003-A1 | COMPLEX FOLATE-NOTA-Ga68 | FOLR1, FOLR2, DHFR | IDO1 1487/4885KMT2A 831/4885MEN1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.