SCHEMBL16587384

SCHEMBL16587384

CC(=O)N(C(C)=O)C(=S)NC(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
GAA P10253 3/20 0.56
KDM4E B2RXH2 1/20 0.56
EPHX1 P07099 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
HTT P42858 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
LMNA P02545 1/20 0.51
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HPGD P15428 2/20 0.49
ALOX12 P18054 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CCR6 P51684 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10400661 0.81 PKM (0.66) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL13645595 0.79 ALDH1A1 (0.65) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL21894455 0.79 ALDH1A1 (0.47) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL16587387 0.77 ALDH1A1 (0.61) ALDH1A1GAAKDM4ESMN1; SMN2HTT
SCHEMBL5451660 0.77 ALDH1A1 (0.68) ALDH1A1GAAKDM4ESMN1; SMN2HTT
SCHEMBL10866755 0.76 ALDH1A1 (0.56) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL19100020 0.74 ALDH1A1 (0.58) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL863064 0.74 ALDH1A1 (0.63) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
SCHEMBL6966315 0.74 ALDH1A1 (0.69) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2
Acetic Acid SCHEMBL28664924 0.74 ALDH1A1 (0.89) ALDH1A1GAAKDM4EEPHX1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612609-B1 ADHESIVE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2022-12-28 EP disclosed
US-10590311-B2 Accelerators for two part curable compositions Henkel IP & Holding GmbH (DE) 2020-03-17 US disclosed
WO-2020035580-A1 TWO STEP ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
WO-2020037195-A1 TWO-PART, CYANOACRYLATE/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2020-02-20 WO disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9371473-B2 Accelerators for two step adhesive systems Henkel IP & Holding GmbH (DE) 2016-06-21 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-9365750-B2 Accelerators for curable compositions Henkel IP & Holding GmbH (DE) 2016-06-14 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed
US-8986847-B2 Accelerator/oxidant/proton source combinations for two part curable compositions Henkel IP & Holding GmbH (DE) 2015-03-24 US disclosed