Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303438 | 0.78 | CYP2A6 (0.50) | CYP2A6L3MBTL1TDP1KDM4EFAAH | |
| SCHEMBL1255190 | 0.77 | CYP2A6 (0.46) | CYP2A6L3MBTL1KDM4EFAAHPRKCI | |
| SCHEMBL25185804 | 0.77 | CYP2A6 (0.49) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB | |
| SCHEMBL6583538 | 0.77 | CYP2A6 (0.49) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB | |
| SCHEMBL111470 | 0.77 | CYP2A6 (0.49) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB | |
| SCHEMBL14473327 | 0.77 | CYP2A6 (0.49) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB | |
| SCHEMBL5204217 | 0.76 | HTR6 (0.49) | TDP1KDM4EPTPRCPTPN1DRD2 | |
| Hydrochloric Acid SCHEMBL27898641 | 0.75 | CYP2A6 (0.47) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB | |
| SCHEMBL31292647 | 0.75 | CACNA1H (0.44) | TDP1KDM4EKDM2B | |
| SCHEMBL6945456 | 0.74 | CYP2A6 (0.46) | CYP2A6L3MBTL1FAAHPRKCIPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359350-B2 | Ring-fused compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-07 | — | — | US | disclosed |
| US-20150203490-A1 | RING-FUSED COMPOUND | SATO PHARMACEUTICAL CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| US-8987473-B2 | Ring-fused compound | SATO PHARMACEUTICAL CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| CN-1077572-C | Substituted bisindolylmaleimides for inhibition of cell proliferation | HOFFMANN LA ROCHE (CH) | 2002-01-09 | — | — | CN | disclosed |
| CN-1226249-A | Substituted bisindolylmaleimides for inhibition of cell proliferation | HOFFMANN LA ROCHE (CH) | 1999-08-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203490-A1 | RING-FUSED COMPOUND | URB2, RCOR1, RCC2 | CYP2A6 1728/4885L3MBTL1 1284/4885TDP1 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.